Heat, age and Millman combine to floor Federer

Novak Djokovic puts an ice towel around his head during a changeover against Joao Sousa during the fourth round of the

Novak Djokovic puts an ice towel around his head during a changeover against Joao Sousa during the fourth round of the

It is also only the second time in Federer's past 14 appearances at the US Open that he has lost before the quarter-finals. "Now I just don't put them in the bag anymore". She said afterward she felt dizzy and was "just asking nature, I don't know, the god, to move the shade".

"John dealt with it better", Federer added.

He responded by taking another break before playing one tournament in Cincinnati, where he lost on the final against Novak Djokovic, in the build-up to the US Open.

"I love his intensity", Federer said of Millman, his summer hitting partner in Switzerland earlier this year.

The Swiss ace said he just wanted to forget the match against Millman as soon as possible. "Today he was definitely not at his best but I'll take it". "But I'll take it".

Sharapova, the 2006 champion, had never lost a night session match in NY prior to her first Grand Slam meeting with Suarez Navarro. The world's No. 2 male player faced John Millman, 29, in the fourth round on September 3, in what would be one of the biggest shockers of this year's tournament.

He squandered two set points in the second set and another in the third set tiebreak as the errors piled up. For men's singles matches, the break would come between the third and fourth sets.

The contest was over shortly before 1 a.m. when he hit a tired forehand wide. "But at the same time, there is a little biological clock that is not really working in your favour", the No. 6-seeded Djokovic told the crowd afterward.

The other quarterfinal on the bottom half of the draw will be 2014 runner-up Kei Nishikori against 2014 champion Marin Cilic or No. 10 David Goffin.

His win in Melbourne was relatively straightforward - the physical demise of his two main rivals Rafael Nadal and Djokovic no doubt playing a big factor - and organisers chose to give him a leg up in the final at the expense of Marin Cilic, who was unaware of plans to begin their epic five-setter under the roof.

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Defending women's champion Sloane Stephens progressed to the quarter-finals but there were losses for Maria Sharapova and Elina Svitolina.

The defeat also ended the former world number one's flawless record of 23 wins - 22 of them on Arthur Ashe Stadium - in night sessions at Flushing Meadows.

"I thought the match was tough".

"It was very hot tonight ... just one of those nights where I guess I felt I couldn't get air", the 20-times major victor said after relinquishing a one-set lead in his 3-6 7-5 7-6 (9-7) 7-6 (7-3) fourth-round loss at Flushing Meadows.

"I didn't take care of the chances that I had". "I felt a little bit guilty because he didn't have his best day. That's been a constant with me ever since I played the game, because, if you do that, you start behind the eight ball straight away".

The 37-year-old Swiss had prioritised winning a sixth title at Flushing Meadows but was beaten 3-6 7-5 7-6 (9-7) 7-6 (7-3) in three hours 35 minutes.

According to the ATP, he had just 49% of first serves - his second-lowest in his 98 US Open matches and fifth-lowest in his career 393 Grand Slam matches.

Then Federer had a set point in the third at 6-5 in the tiebreaker, but again was stymied.

"It's not easy", Djokovic said, "to play in these kind of conditions".

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