The Second Person Ever To Be Cured Of HIV: "The London Patient"

World’s second man cleared of AIDS virus invigorates quest for cure

World’s second man cleared of AIDS virus invigorates quest for cure

HIV is a virus spread through bodily fluids that attacks the immune system, specifically CD4 cells, according to HIV.gov. The United Nations estimates that 37 million people worldwide are living with HIV.

Over a decade ago, a German doctor announced the first case of a patient who had been cleared of the virus.

The breakthrough, which is detailed in a new paper in Nature, utilized the natural HIV-fighting power of a mutation called "CCR5 delta 32" which makes certain people resistant to the virus. Although the patient has been in remission and has not taken any antiretroviral drugs for 18 months, his doctors say it's still too early to claim he's been "cured".

Gupta added that the method used is not appropriate for all patients but offers hope for new treatment strategies, including gene therapies.

But the team emphasized that it is too early to say with certainty that the patient has been cured of HIV, and that they will continue to monitor the patient's condition. Until now, Brown is the only person thought to have been cured of infection with HIV, the virus that causes AIDS.

In 2012, he was diagnosed with advanced Hodgkin's Lymphoma. Scientists have wondered, however, whether this good fortune could be shared around by injecting stem cells from people with two Δ32 copies into HIV patients. He and Brown are the only cases of long-term HIV remission ever recorded.

But it in the past 18 months he was taken off the extra drugs and regular testing confirmed his viral load is now undetectable.

Researchers dubbed the original patient cured of HIV "the Berlin patient", though he was later revealed to be Timothy Ray Brown, a 52-year-old man who now lives in California. His transplant beat cancer without any threatening side-effects, and the transplanted immune cells that were made resistant to HIV appeared to have replaced all the HIV-vulnerable cells in his blood. The man, nicknamed The London Man, was said to have contracted the HIV virus in 2003.

Republicans deny mocking victims with pearls
A handful of male lawmakers wore pearl necklaces as activists testified about their experiences with gun violence. Chris Sununu with pearls after he signed the concealed carry bill into law, The Union Leader added.

For now, the patient has chosen to remain anonymous and he's being called the "London Patient". Instead, they say the patient is in remission.

Anton Pozniak, president of the International AIDS Society (IAS) said the announcement "reaffirms our belief that there exists a proof of concept that HIV is curable". The patient was receiving the bone marrow transplant for cancer. In this case, the patient had an HIV infection for almost a decade that was being kept in check with antiviral therapies that were tailored to his virus' genotype.

Sharon Lewin, director of the Peter Doherty Institute for Infection and Immunity in Melbourne and a leading expert on HIV/AIDS, told AFP it was likely one of two things had happened.

The transplant was complicated by a mild case of graft-vs-host disease, which is similar to the first patient to achieve HIV remission. But with the mutated CCR5, Brown's immune cells became molecular fortresses that HIV couldn't penetrate - which meant the transplant essentially cured him of his infection.

12 years ago, there was Timothy Ray Brown, also known as the Berlin patient.

Wensing heads a consortium of European scientists who work with stem cells transplanted into patients with HIV in attempts to find a cure, according to TheNYT.

The patient has not been identified.

Recommended News

  • Springfield's Convoy of Hope responds to deadly tornado devastation in Alabama

    Springfield's Convoy of Hope responds to deadly tornado devastation in Alabama

    Lee-Scott Academy Family and Friends, With sadness this morning, we share that Taylor Thornton , a 4th grader at... Based on the damage, they've determined that it was EF-4 tornado with 170 miles per hour (274 kph) winds.
    DNC rejects Fox News request to televise Democratic 2020 debates

    DNC rejects Fox News request to televise Democratic 2020 debates

    The alleged attempt was seen as an effort to retaliate against CNN for its critical reporting on the Trump administration. NBC already has been announced to host the the first Dem debate this summer; CNN will host the second.
    Last auto  to roll off assembly line at Ohio GM plant

    Last auto to roll off assembly line at Ohio GM plant

    Long term disposition of the facility will be determined after the UAW-GM contract negotiations later this year. Lordstown's history dates to 1966.
  • The Sinner season 3 in the works with Matt Bomer

    The Sinner season 3 in the works with Matt Bomer

    An Emmy nominee and Golden Globe victor for the HBO movie The Normal Heart , Bomer starred on the Amazon series The Last Tycoon . Intended as an eight-episode limited series, the show was so well-received that USA Network chose to continue with new seasons.
    Father guilty of acid attack plot against three-year-old son

    Father guilty of acid attack plot against three-year-old son

    Jonathan Rees QC said the father was the "driving force" behind the attack. "The family had been shopping for a birthday present". CCTV also showed Pulko carrying what the court heard was a bottle of acid while walking next to the mother and her two sons.
    Three bombs found at London transport hubs

    Three bombs found at London transport hubs

    The stamps on the envelope have pictures of hearts and resemble ones issued by Ireland's post office for Valentine's Day 2018. No person or group claimed responsibility for sending the devices and police said they haven't made any arrests.
  • Radio Stations Around The World Ban Michael Jackson

    Radio Stations Around The World Ban Michael Jackson

    Meanwhile, BBC recently denied banning Jackson following a report that said BBC Radio 2 had "quietly dropped" Jackson's songs from their playlists.
    Arzoo Govitrikar Files Domestic Abuse Complaint Against Husband

    Arzoo Govitrikar Files Domestic Abuse Complaint Against Husband

    Inspector Sukhlal Verpe from Worli Police Station refused to comment on the complaint and the status of investigation. In her complaint, the actress alleged she was manhandled by her husband often and also verbally abused her for months.
    Uber 'not liable' for self-driving death

    Uber 'not liable' for self-driving death

    In December, Uber filed confidentially for an initial public offering and is expected to seek a valuation of up to $120 billion. The potential for a corporation to be charged with manslaughter raises multiple issues of novelty and legal first impressions.
  • Trudeau's Regina events cancelled: PMO

    Trudeau's Regina events cancelled: PMO

    I think it's shocking to a lot of Canadians to see inside how cabinet and the (Prime Minister's Office) works", Rusnak told CKPR Radio.
    In 5 hours Borussia Dortmund coach Favre demands better from flat Sancho

    In 5 hours Borussia Dortmund coach Favre demands better from flat Sancho

    The club are also said to be tracking Napoli central defender Kalidou Koulibaly and want to add another midfielder to the squad. The former Manchester City winger has faltered as Dortmund have, with the team winning just one of their last six games.
    Trebek says he has pancreatic cancer

    Trebek says he has pancreatic cancer

    The beloved trivia mediator has been honored with awards and recognition many times over for his contributions to pop culture. There were no other details on his health status or the future of the show as he undergoes treatment.

We are pleased to provide this opportunity to share information, experiences and observations about what's in the news.
Some of the comments may be reprinted elsewhere in the site or in the newspaper.
Thank you for taking the time to offer your thoughts.