Federer cruised at Roland Garros
Nadal's domination of the French Open began when he lifted La Coupe des Mousquetaires on his debut as a teenager in 2005, and he is pleased to have displayed greater longevity than many thought was possible.
The 20-year-old Tsitsipas missed out on the chance for a rematch with Federer, having beaten the 20-time major title victor in the Australian Open fourth round earlier this year.
Despite leading Wawrinka, 23-3, in career head-to-head meetings, Federer said he still remembers his quarterfinal loss to his friend in Paris four years ago.
Federer, the 2009 champion in Paris, is the oldest man to make the quarter-finals of a Slam since Jimmy Connors at the 1991 US Open.
Japan's Kei Nishikori, the seventh seed, ran into trouble in his clash with Serbia's Laslo Djere before edging a five-setter 6-4, 6-7 (6-8), 6-3, 4-6, 8-6 in four hours and 26 minutes.
"You can't expect you're going to play quarter-finals in a Grand Slam, but I played some tough matches", said Vondrousova. Federer also became the third-oldest man to reach the last eight at Roland Garros.
They were playing their fourth-round match Sunday on neighboring Court Suzanne Lenglen.
Spanish 19th seed Muguruza eased to a 6-3, 6-3 victory on Chatrier to reach the fourth round for the sixth successive year and set up a tie with either last year's runner-up Sloane Stephens or Slovenian Polona Hercog.
Sir Elton John condemns removal of gay scenes from Rocketman in Russian Federation
Instead the edited film simply says he founded an AIDS foundation and continues to work with his musical partner, Bernie Taupin. The closing credits had also been amended to drop references to John's relationship with husband David Furnish.
The Swiss moves into the quarterfinals for the fifth time in his career, and first time since reaching the final in 2017.
She will play Croatia's Petra Martic, who rallied from a set down to beat Estonian Kaia Kanepi 5-7 6-2 6-4 and reach her first Grand Slam quarter-final. Konta's quarterfinal opponent will be US.
Reigning champion Nadal continued his bid for a record-extending 12th Roland Garros title by beating Grand Slam debutant Juan Ignacio Londero 6-2, 6-3, 6-3.
The 28-year-old booked her place in the last eight of a Grand Slam for the first time with a 5-7, 6-2, 6-4 victory, recovering breaks of serve in both the second and third sets.
He has beaten Lorenzo Sonego, Oscar Otte and Casper Ruud, ranked 74th, 144th and 63rd in the world respectively without dropping a set, and Mayer never looked likely to improve on his three previous defeats at Federer's hands.
With his eyes fixed firmly on claiming a 12th French Open title next Sunday he seemed eager to finish the job swiftly, but after moving 4-1 ahead in the third set he dropped serve for the first time in the match.
Nadal's pace appeared to drop ever so slightly and Londero even sensed another break two games later when heavy hitting got him to 0-30 on the second seed's serve, but Nadal reeled off four consecutive points, holding with an ace.
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