Quitting smoking reverses lung cell damage even for decade-long smokers

Quitting smoking reverses lung cell damage even for decade-long smokers

Quitting smoking reverses lung cell damage even for decade-long smokers

US Centres for Disease Control and Prevention classifies cigarette smoking as the number one risk factor for lung cancer.

An editorial that accompanied the study said that it backs the results of an earlier USA trial that found a 20 percent drop in lung cancer deaths via screenings with CT in comparison to chest X-rays.

However, after someone quits smoking, it is these cells that grow and replace the damaged cells in the lungs.

Smokers can effectively turn back time in their lungs by kicking the habit, with healthy cells emerging to replace some of their tobacco-damaged and cancer-prone ones, a new study shows. Although women were under-represented in the study, the research team found that screening lowered their risk of dying from lung cancer by 33%.

At the event the UCH Cancer Fund and Haematology Cancer Care - the key UCLH Charity funds supporting cancer services at UCLH - will showcase the difference the funds have made to patient care and staff experience. The participants included current smokers, ex-smokers, adults who had never smoked and children.

Dr. Kate Gowers, joint first author from UCL, said: "Our study is the first time that scientists have looked in detail at the genetic effects of smoking on individual healthy lung cells".

"What is so exciting about our study is that it shows that it's never too late to quit-some of the people in our study had smoked more than 15,000 packs of cigarettes over their life, but within a few years of quitting, numerous cells lining their airways showed no evidence of damage from tobacco".

Overall, up to 40% of the lung cells in ex-smokers were healthy - compared to less than 10% in the current smokers.

There are 12,000 new cases of lung cancer and over 9,000 deaths from the disease each year, with the disease often discovered in the advanced stage, reducing the treatments available and resulting in its high mortality rate. "There is a population of cells that, kind of, magically replenish the lining of the airways".

The examination dissected lung biopsies from 16 individuals, including current smokers, ex-smokers, grown-ups who had never smoked and kids, searching for the changes that can prompt malignancy.

Billie Eilish Asks Fans to Stop Impersonating Her: 'It's Not Safe'
You have been commenting on the video session I did yesterday, and I would like to respond", he wrote in the caption. This was not the first time YouTubers have turned to stunts with Eilish impersonators for video content.

They then sequenced the DNA from 632 cells and came out with the findings that "surprised" them.

When compared to non-smokers, 9 out of 10 lung cells in active smokers, in spite of not being cancerous, exhibited almost 10,000 mutations or changes.

But a small proportion of cells went unscathed.

"There are now three national screening programs for cancer in Australia and they are for bowel, breast and cervical cancers, all of which have better survival [rates] than lung cancer", Professor Keefe said.

The leading cause of cancer death in Australia, lung cancer is 2.1 times more likely to be diagnosed in Aboriginal and Torres Strait Islanders, who are 1.8 times more likely to die from the cancer than their non-Indigenous counterparts.

Unexpectedly, in people who had stopped smoking, there was a sizable group of cells lining the airways that had escaped the genetic damage from their past smoking.

The research, published today (Jan 30) is part of the £20m Mutographs of Cancer project, a Cancer Research UK Grand Challenge initiative. This damage is not reversible, even after stopping smoking.

"If we can work out where they normally live and what makes them expand when someone stops smoking, perhaps we have opportunities to make them even more effective at fix".

"The results add to existing evidence that, if you smoke, stopping completely is the best thing you can do for your health".

Recommended News

  • Health experts warn China travel ban would hinder coronavirus response

    Health experts warn China travel ban would hinder coronavirus response

    The first quarantines of USA citizens potentially exposed to coronavirus in China began hours before the White House announcement. World Health Organization spokesman, Christian Lindmeier, says closing borders will not keep out the virus.
    CDC confirms 8th coronavirus case in the U.S.

    CDC confirms 8th coronavirus case in the U.S.

    Japan and Germany also advised against non-essential travel to China and Britain did as well, except for Hong Kong and Macao. Indonesia also sent a plane, sparking rowdy protests from residents living near a military base that will house evacuees.
    Wireless carriers violated users' privacy with location sharing, FCC says

    Wireless carriers violated users' privacy with location sharing, FCC says

    An official documentation of how these companies violated the law will be delivered shortly. I am happy we will finally act on those egregious allegations.
  • Andy Gill Dead - Gang of Four Guitarist Dies at 64

    Andy Gill Dead - Gang of Four Guitarist Dies at 64

    No cause of death was given, but they said Gill had spent time in hospital since coming off tour in November. It was named by Rolling Stone journal in 2003 as one of the 500 best albums ever.

    NYC reports first person under investigation for coronavirus

    There have been eight confirmed cases of novel coronavirus in the United States and over 12,000 worldwide. The other U.S. cases are California (three), IL (two) and one each in Washington state and Arizona.
    Brexit 50p Coins Enter Circulation as Britain Bids Farewell to EU

    Brexit 50p Coins Enter Circulation as Britain Bids Farewell to EU

    Andrew Hagger, of Moneycomms, an analyst firm, said: "The market will be flooded with them and there will be no rarity value". Contained in that set - priced at £30 - is a 1973 50p coin marking the UK's membership to the European Economic Community.
  • Boston man confirmed to have coronavirus

    Boston man confirmed to have coronavirus

    But the toll keeps mounting, with health authorities in Hubei on Sunday reporting 45 more deaths in the preceding 24 hours. State Department issued what it calls a Level 4-Do Not Travel advisory, and also recommended Americans now in China leave.
    Apple completes rollout of redesigned Apple Maps in the US

    Apple completes rollout of redesigned Apple Maps in the US

    Apple Maps, now utilized in over 200 nations, can be found on iPhone, iPad, Mac, Apple Watch and in automobiles through CarPlay . These favorited destinations will appear on the Apple Maps launch screen where they can be quickly tapped for immediate routes.
    Alibaba’s Jack Ma donates $14 million to develop coronavirus vaccine

    Alibaba’s Jack Ma donates $14 million to develop coronavirus vaccine

    A single strain of DNA is the main ingredient in this vaccine which they hope will trigger a strong response against the virus. The final time a comparable virus - Sars - emerged in 2002 - China was sluggish to let the world know what was occurring.
  • Lamar Jackson joins Tom Brady as unanimous NFL MVP

    Lamar Jackson joins Tom Brady as unanimous NFL MVP

    He only threw six interceptions in the regular season, just one of which came after the Steelers game on October 6. Jackson's 1,206 yards also landed him at sixth place in the entire National Football League in rushing yards.
    Man who works at coronavirus-hit firm is Germany's seventh case

    Man who works at coronavirus-hit firm is Germany's seventh case

    Earlier on Friday, Germany confirmed that a child of one of the sickened Webasto employees had tested positive for the virus. Other illnesses in Germany were disclosed during the course of the week.
    World Health Organization  declares coronavirus outbreak ‘global emergency’: Here is what it means

    World Health Organization declares coronavirus outbreak ‘global emergency’: Here is what it means

    Thousands of factory workers now on Lunar New Year holidays may struggle to get back to work next week due to travel restrictions. In addition to that, there is now confirmed cases of human-to-human transmission of the virus in 3 countries outside of China.

We are pleased to provide this opportunity to share information, experiences and observations about what's in the news.
Some of the comments may be reprinted elsewhere in the site or in the newspaper.
Thank you for taking the time to offer your thoughts.