University Of Pittsburgh Scientists Create Potential Coronavirus Vaccine

Experts have raised hopes that a vaccine could be ready in as little as 18 months

Experts have raised hopes that a vaccine could be ready in as little as 18 months

As a result of the expediency of the research, trials and production, CoroFlu could be tested in human clinical trials by fall 2020, according to the news release. So far, the researchers say that mice given the SARS-CoV-2 variation have been following the same trend.

It is the first peer-reviewed antidote to the coronavirus and is delivered through a "painless" jab similar to a flu shot.

"We're still sticking to the optimistic 18 months for delivery of vaccine to the general consumers", Rob Grenfell, the Commonwealth Scientific and Industrial Research Organisation's (CSIRO) director of health, told Reuters.

"This particular situation is different to any other we've ever seen, so we do not know how long it will take the process of clinical development", added the researcher.

They were able to act on this study fast because they already laid out all the groundwork that was needed to be done when the coronavirus was still at its early stage of the outbreak.

"CoroFlu will also express the influenza virus hemagglutinin protein, which is the major influenza virus antigen, so we should get immune responses to both coronavirus and influenza", Neumann said the news release.

"We had previous experience on SARS-CoV in 2003 and MERS-CoV in 2014. Researchers have progressed to studying the course of infection in animals, a crucial step in understanding if a vaccine will work".

We said it before in this space, but it bears repeating after listening to Gambotto on Thursday - pandemic research needs to be a national priority.

While there is an experimental mRNA COVID-19 vaccine candidate under investigation, the vaccine described in EBioMedicine uses laboratory developed pieces of viral protein to induce immunity.

Three more coronavirus deaths at York Hospital NHS Trust
The Health Secretary has also paid tribute to the "hard work and dedication" of staff working on the hospitals across the country. The military helped to set up London's Nightingale hospital, which has 500 beds in place with space for another 3,500.

The potential vaccine uses a needle patch design, called a microneedle array, to increase its potential potency.

This consists of a patch of the size of the tip of a finger with 400 needles can be too small to manage the parts of the protein "spike" in the skin where the immune reaction is stronger. It is created to be delivered by a microneedle array, a patch of 400 extremely fine needles composed of just sugar and the protein antigens.

"We developed this to build on the original scratch method used to deliver the smallpox vaccine to the skin, but as a high-tech version that is more efficient and reproducible patient to patient", said study co-author Louis Falo, professor and chair of dermatology.

A "cell factory" produces multiple layers of cultured cells engineered to grow the spike protein, that can be stacked further to multiply the yield.

"We are carefully balancing operating at speed with the critical need for safety in response to this global public health emergency", said Drew, who is leading CSIRO's COVID-19 virus and vaccine work.

Once manufactured, the vaccine can be stored at room temperature, which eliminates the need for refrigeration during transport and storage.

The Pittsburgh Coronavirus Vaccine is called PittCoVacc.

"Based on its unique dual mechanism of action, APN01 has the potential to be the first drug approved to treat COVID-19 that specifically targets the new SARS-CoV-2 virus", said Peter Llewellyn-Davies, Chief Executive Officer of Apeiron Biologics.

UW predicts $100 million loss due to COVID-19 pandemicThe University of Wisconsin is expecting a $100 million loss due to the ongoing COVID-19 crisis, according to the Wisconsin Read...

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