Moderna Will Likely Announce Efficacy of COVID-19 Vaccine in November - CEO

AstraZeneca denies vaccine trial subject had nerve ailment

AstraZeneca denies vaccine trial subject had nerve ailment

A Russian agency and an Indian pharma company announced on Wednesday their plans to conduct an efficacy trial of the Russian candidate vaccine against the coronavirus disease in India and distribute 100 million doses for mass vaccination campaigns. About 28 percent of participants are people of color. If the vaccine does not reach the efficacy mark after 53 cases, the data safety and monitoring board will take another interim look at the data after 106 cases, and a final look after 151 people in the trial become infected with the virus. Volunteers receive two shots four weeks apart. These are: Gamaleya/Sputnik, Pfizer, AstraZeneca, Moderna and Sinovac. Union Health Minister Harsh Vardhan said in Rajya Sabha on Thursday that the coronavirus vaccine will be made available in the country by the start of next year.

Pfizer, the other American company currently carrying out Phase 3 trials in the United States, followed suit a short time later and there is now added pressure for the remainder to do the same.

Pfizer has about 2,400 employees in MA, including about 1,400 at a plant in Andover that is helping to manufacture the mRNA vaccine. But the USA government's Operation Warp Speed program has given the company nearly $1 billion for its work on a vaccine.

On the call, the company said it is on track to deliver 500 million to 1 billion doses of the vaccine annually.

In a presentation to investors on Tuesday, Pfizer Inc said the company has enrolled more than 29,000 people in its 44,000-volunteer trial to test an experimental COVID-19 vaccine the company is developing with German partner BioNTech. That could come quickly.

Unlike other drug makers, Pfizer is not receiving money from the US government for its vaccine research.

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The report said even if all five vaccines are approved, their combined production capacity is enough for only about three billion people since each person is likely to need two doses.

Bancel said if everything went well the company could deliver about 100 million doses of vaccine to the U.S. government in the "first few months of 2021". Despite this, the organisation said that Moderna intends to make a profit and has sold its supply at $12 to $16 [between Rs 800 to Rs 1,200] in the United States, and for about $35 [approximately Rs 2,500] in other countries.

With a previous commitment of as much as $955 million from the federal Biomedical Advanced Research and Development Authority, or BARDA, the government has pledged up to $2.48 billion for Moderna's vaccine candidate. It is one of several COVID-19 vaccine candidates being bankrolled by the government. The requirements appear to be those from drug-makers Pfizer and Moderna.

Bancel acknowledged that government funding "comes with obligations" for Moderna, including frequent discussions with government officials about how the biotech is usingthe money and what progress the firm is making.

"We do not allege misconduct, we just want them to provide additional data", said Dr. Konstantin Andreev, one of the signatories and a microbiologist and biophysicist affiliated with the Howard Hughes Medical Institute and Northwestern University.

The agreement brings the total number of doses Russian Federation has so far announced that it will supply overseas to just over 200 million - half to Latin America and half to India.

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